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KMID : 0359719940120020270
Journal of the Korean Neurological Association
1994 Volume.12 No. 2 p.270 ~ p.278
Magnetic motor evoked potential in non-insulin dependent diabetic patients




Abstract
Diabetes mellitus is the most comon cause of the peripheral neuropathy and an important risk factor of the cerebrovascular disease. There are also several case reports of the diabetic myelopathy, and it has been known that the incidence of cord
involvement is not rare on autopsy and somatosensory evoked potential studies.
To determine the functional derangement of central desecending motor pathway in diabetes, 59 cases of diabetes were studied with the magnetic motor evoked potential (MMEP) study. The diabetic patients were divided into two groups according to the
nerve
conduction study (23 with normal and 36 with abnormal nerve conduction studies) and compared with the results of 31 normal control cases.
1. At each stimulated point, there are statistically significant differences in latencies of MMEPs between normal control and diabetic groups.
2. Compared to the control group, the peripheral conduction time is also significantly prolonged in diabetic patients
3. However, there is no difference in the calculated central motor conduction time among three groups.
In conclusion, this result means that prolonged latencies of MMEPs in diabetes nay be due to peripheral neuropathy rather than dysfunction of central motor pathway. Therefore the clinical significance of MMEP has to be decided segmentally rather
than
by simple determination of the vertex latency.
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